Description
SS-31 Technical Overview
SS-31, also known as Elamipretide or MTP-131, is a synthetic tetrapeptide investigated for its association with mitochondrial membranes.
The peptide contains alternating positively charged and aromatic residues and has been studied for interactions with cardiolipin, a phospholipid enriched in the inner mitochondrial membrane.
Experimental research has examined mitochondrial membrane organization, oxidative stress, respiratory function, and cellular bioenergetics following exposure to SS-31.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | SS-31 |
| Alternative Names | Elamipretide, MTP-131, Bendavia |
| Classification | Mitochondria-associated tetrapeptide |
| Sequence | D-Arg-Dmt-Lys-Phe-NH2 |
| Sequence Length | 4 residues |
| Modified Residue | Dmt: 2,6-dimethyltyrosine |
| Research Focus | Cardiolipin-associated mitochondrial membranes |
| Vial Content | 10mg |
Storage and Handling
- Follow the manufacturer’s stability recommendations.
- Protect from moisture and contamination.
- Use suitable laboratory peptide handling procedures.
Lyophilized Format
SS-31 may be supplied as a lyophilized peptide. Stability depends on formulation and storage conditions.
Research Use Disclaimer
This Peptide Lives research preparation is not represented as an approved pharmaceutical product and is not intended for human or veterinary administration.
Frequently Asked Questions
What Is SS-31?
A synthetic tetrapeptide associated with mitochondrial membrane research.
What Is Elamipretide?
Another name for SS-31.
What Is Cardiolipin?
A phospholipid enriched in the inner mitochondrial membrane.
What Research Areas Involve SS-31?
Mitochondrial bioenergetics, membrane organization, and cellular stress pathways.
SS-31 Research Overview
SS-31 has been investigated in experimental models of mitochondrial function and membrane-associated cellular processes.
Cardiolipin Research
Studies have examined interactions between SS-31 and cardiolipin-containing membranes.
Mitochondrial Bioenergetics
Experimental investigations have evaluated respiratory measurements and mitochondrial energy-related pathways.
Cellular Stress Research
Research has examined SS-31-associated changes in mitochondrial responses to experimental stress.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Cardiolipin Research | Membrane binding assays |
| Mitochondrial Biology | Respiration studies |
| Cellular Bioenergetics | Metabolic pathway measurements |
References
- Szeto HH. (2014). First-in-Class Cardiolipin-Protective Compound as a Therapeutic Agent to Restore Mitochondrial Bioenergetics. British Journal of Pharmacology. Publication information.
Certificate of Analysis (COA)
Analytical documentation should identify the peptide’s exact structure, salt form, purity, and content.
Reviews
There are no reviews yet.