Description
Epithalon Technical Overview
Epithalon, also known as Epitalon or AEDG peptide, is a synthetic tetrapeptide composed of alanine, glutamic acid, aspartic acid, and glycine.
It belongs to a group of short peptide bioregulators investigated in experimental studies of cellular aging, telomerase activity, chromatin organization, and gene expression.
Laboratory research has examined Epithalon-associated changes in telomerase activity in selected human cell cultures. These findings do not establish that the peptide reverses human aging or extends human lifespan.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | Epithalon |
| Alternative Names | Epitalon, AEDG |
| CAS Number | 307297-39-8 |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | 390.35 g/mol |
| Sequence | H-Ala-Glu-Asp-Gly-OH |
| One-Letter Sequence | AEDG |
| Sequence Length | 4 amino acid residues |
| Classification | Short peptide bioregulator |
| Vial Content | 10mg |
Storage and Handling
- Follow manufacturer stability recommendations.
- Protect from moisture and direct light.
- Use appropriate laboratory peptide handling procedures.
Lyophilized Format
Epithalon may be prepared in lyophilized form. The stability of the material depends on its formulation and storage conditions.
Research Use Disclaimer
Epithalon is not FDA-approved for human therapeutic use. Intended exclusively for laboratory investigation.
Frequently Asked Questions
What Is Epithalon 10mg?
A research preparation of the AEDG tetrapeptide.
What Is Its Amino Acid Sequence?
Ala-Glu-Asp-Gly.
What Is Telomerase?
An enzyme involved in maintaining telomeric DNA sequences.
Is Epithalon the Same as Epithalamin?
No. Epithalon is a defined tetrapeptide; Epithalamin is a complex peptide preparation.
Has Epithalon Been Proven to Extend Human Lifespan?
No.
Epithalon Research Overview
Epithalon has been investigated in experimental models examining molecular mechanisms associated with cellular aging.
Telomerase Research
Selected cell culture studies have reported changes in telomerase activity following Epithalon exposure.
Chromatin Research
Investigations of short peptide bioregulators have examined relationships with chromatin-associated cellular processes.
Gene Expression Research
Research has explored possible interactions between defined short peptides and transcription-related mechanisms.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Telomerase Research | Enzyme activity assays |
| Chromatin Biology | Molecular organization studies |
| Gene Expression | Transcriptional analysis |
| Peptide Chemistry | Tetrapeptide characterization |
References
- Khavinson VK, Bondarev IE, Butyugov AA. (2003). Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. Bulletin of Experimental Biology and Medicine. Publication information.
Certificate of Analysis (COA)
Documentation should confirm the AEDG sequence, peptide identity, purity, and actual content.
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