Description
Pinealon Technical Overview
Pinealon, also known as the EDR peptide, is a synthetic tripeptide consisting of L-glutamic acid, L-aspartic acid, and L-arginine.
It belongs to a family of short peptide bioregulators investigated in experimental studies involving cellular signaling, neuronal stress responses, gene regulation, and age-associated cellular processes.
Pinealon has a minimal linear structure consisting of three amino acid residues. Its defined chemical composition makes it relevant to research examining relationships between short peptide sequences and cellular regulatory mechanisms.
Published experimental work involving Pinealon and related peptides has explored neuronal cell responses and molecular processes associated with cellular stress. The evidence remains largely preclinical.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | Pinealon |
| Alternative Names | EDR Peptide, Glu-Asp-Arg |
| Chemical Name | L-Glutamyl-L-aspartyl-L-arginine |
| CAS Number | 175175-23-2 |
| Amino Acid Sequence | H-Glu-Asp-Arg-OH |
| One-Letter Sequence | EDR |
| Sequence Length | 3 amino acid residues |
| Molecular Formula | C15H26N6O8 |
| Molecular Weight | 418.40 g/mol |
| Peptide Structure | Linear tripeptide |
| Peptide Classification | Short peptide bioregulator |
| Source | Synthetic |
| Vial Content | 20mg |
| Research Category | Neuronal and Peptide Bioregulation Research |
Molecular specifications describe the unmodified Glu-Asp-Arg peptide. Salt forms and other formulations may have different overall chemical compositions.
Storage and Handling
- Store according to manufacturer-provided stability recommendations.
- Keep the container protected from moisture and unnecessary light exposure.
- Minimize temperature fluctuations.
- Follow established laboratory handling procedures.
Lyophilized Format
Pinealon may be manufactured in lyophilized form. Freeze-drying can reduce moisture content and support stability under appropriate conditions. The actual physical form and storage requirements of this preparation require manufacturer confirmation.
Research Use Disclaimer
Pinealon is described exclusively for laboratory investigation. It is not FDA-approved for human therapeutic use and is not intended for human or veterinary administration.
Frequently Asked Questions
What Is Pinealon 20mg?
Pinealon 20mg is a research preparation of the synthetic tripeptide Glu-Asp-Arg.
What Is the Amino Acid Sequence?
The sequence is H-Glu-Asp-Arg-OH, abbreviated EDR.
What Are the CAS Number and Molecular Weight?
Pinealon has CAS number 175175-23-2 and a molecular weight of approximately 418.40 g/mol.
What Research Areas Involve Pinealon?
Research includes short peptide bioregulation, neuronal cellular responses, gene regulation, and experimental stress signaling.
Is Pinealon Approved for Human Use?
No. Pinealon is not FDA-approved for therapeutic use.
Research Overview
Pinealon has been investigated as part of research into short synthetic peptide bioregulators. The Glu-Asp-Arg sequence is of interest because short peptides can be studied as defined chemical structures in cellular and molecular models.
Research involving Pinealon has explored proposed relationships with neuronal stress signaling and cellular regulatory responses. The precise molecular mechanisms remain incompletely characterized.
Neuronal Cell Research
Experimental investigations have examined Pinealon in neuronal-related models. Proposed neuroprotective responses remain subjects of preclinical research.
Cellular Stress Response Research
Researchers have explored whether short peptide exposure influences cellular responses to oxidative and metabolic stress.
Gene Regulation Research
Studies of short peptide bioregulators have investigated possible relationships between peptide structure and transcription-related molecular processes.
Specific direct regulatory mechanisms attributed to Pinealon require further independent confirmation.
Short Peptide Structure Research
The three-residue EDR sequence provides a defined structure for investigating peptide chemistry, molecular interactions, and physicochemical characteristics.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Neuronal Research | Neuronal cell response assays |
| Cellular Stress | Experimental stress-response measurements |
| Peptide Chemistry | Structural characterization |
| Gene Regulation | Experimental transcription-related studies |
References
- Fedoreyeva LI, Kireev II, Khavinson VKh, Vanyushin BF. (2011). Penetration of Short Fluorescence-Labeled Peptides into the Nucleus in HeLa Cells and In Vitro Specific Interaction of the Peptides with Deoxyribooligonucleotides and DNA. Biochemistry (Moscow). DOI: 10.1134/S0006297911110022.
Research Evidence Note: This publication investigates Pinealon alongside other short peptides in molecular and cellular experiments. It does not establish neuroprotective or cognitive benefits in humans.
Certificate of Analysis (COA)
Researchers should verify the amino acid sequence, molecular identity, purity, and actual peptide content using batch-specific analytical documentation.
For available documentation, contact Peptide Lives.
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