Description
Selank Technical Overview
Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin. Its sequence consists of the tuftsin-related Thr-Lys-Pro-Arg fragment extended with Pro-Gly-Pro.
Selank has been investigated in experimental research involving neurochemical signaling, gene expression, immune-associated pathways, and behavioral responses in animal models.
Some studies have explored its relationship with anxiety-associated behavior and neurotransmitter systems. These findings should not be interpreted as evidence of established anxiolytic efficacy for research-grade Selank preparations.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | Selank |
| Peptide Classification | Synthetic tuftsin-derived heptapeptide |
| Amino Acid Sequence | H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH |
| One-Letter Sequence | TKPRPGP |
| Sequence Length | 7 residues |
| Parent-Related Peptide | Tuftsin |
| Source | Synthetic |
| Vial Content | 5mg |
| Research Category | Neuropeptide Research |
Specifications refer to unmodified Selank. N-acetylated or amidated Selank derivatives are chemically distinct compounds.
Storage and Handling
- Follow manufacturer-provided stability conditions.
- Protect from moisture, direct light, and contamination.
- Minimize temperature fluctuations during storage.
Lyophilized Format
Selank may be prepared in lyophilized form. Physical form and formulation stability should be confirmed for the supplied batch.
Research Use Disclaimer
Selank is not FDA-approved for human therapeutic use. This material is intended exclusively for laboratory research and not for human or veterinary administration.
Frequently Asked Questions
What Is Selank?
Selank is a synthetic seven-amino-acid peptide derived from the tuftsin-related peptide sequence.
What Is Its Sequence?
Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP).
Is Selank the Same as N-Acetyl Selank Amidate?
No. N-terminal acetylation and C-terminal amidation create a chemically modified derivative.
What Research Areas Involve Selank?
Neurochemical signaling, experimental behavior, gene expression, and immune-associated signaling.
Is Selank FDA-Approved?
No. It is not FDA-approved for human therapeutic use.
Research Overview
Selank emerged from research into short peptide analogues related to tuftsin. Experimental investigations have examined its effects on biological signaling and behavioral measurements.
Neurochemical Signaling Research
Animal studies have investigated Selank-associated changes in neurotransmitter-related pathways and behavioral responses.
Gene Expression Research
Experimental investigations have examined changes in the expression of selected genes following exposure to Selank.
Immune Signaling Research
Selank’s structural relationship to tuftsin has supported research involving immune-associated regulatory pathways.
Behavioral Research
Published animal studies have explored stress- and anxiety-associated experimental responses. Human clinical conclusions remain limited.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Peptide Chemistry | Tuftsin analogue characterization |
| Gene Expression | Transcriptional response assays |
| Neurochemical Research | Cellular signaling studies |
| Immune Research | Selected immune-cell signaling assays |
References
Certificate of Analysis (COA)
Batch documentation should identify the exact Selank sequence, terminal groups, purity, and peptide content.



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