Description
GHK-Cu Technical Overview
GHK-Cu is a copper-associated complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK).
The peptide has been investigated in research involving copper binding, fibroblast biology, extracellular matrix regulation, and collagen-associated cellular pathways.
Laboratory studies have also examined changes in gene expression associated with GHK and GHK-Cu exposure. These results provide a basis for studying short peptide-metal complexes in cellular biology.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | GHK-Cu |
| Parent Peptide | Gly-His-Lys |
| One-Letter Sequence | GHK |
| Sequence Length | 3 residues |
| Metal Component | Copper |
| Classification | Copper-binding tripeptide complex |
| Research Category | Skin and Extracellular Matrix Research |
| Vial Content | 50mg |
Storage and Handling
- Follow manufacturer-recommended storage conditions.
- Protect from moisture, excessive light, and contamination.
- Consider copper coordination chemistry when evaluating formulation compatibility.
Lyophilized Format
GHK-Cu may be manufactured in lyophilized form. Stability and appearance depend on the copper complex and formulation.
Research Use Disclaimer
This GHK-Cu preparation is not represented as an FDA-approved therapeutic product. For laboratory research only; not intended for human or veterinary administration.
Frequently Asked Questions
What Is GHK-Cu?
A copper complex of the Gly-His-Lys tripeptide.
What Is Its Amino Acid Sequence?
GHK.
What Is the Difference Between GHK and GHK-Cu?
GHK is the parent peptide; GHK-Cu is its copper-associated complex.
What Research Areas Involve GHK-Cu?
Fibroblast biology, extracellular matrix research, and peptide-metal chemistry.
GHK-Cu Research Overview
GHK-Cu has been studied in experimental connective tissue and cellular signaling research.
Fibroblast Research
Studies examine fibroblast-associated cellular responses.
Extracellular Matrix Research
Research investigates collagen-related pathways and matrix regulation.
Gene Expression Research
Experimental work has evaluated transcriptional changes associated with GHK exposure.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Fibroblast Biology | Cellular signaling assays |
| Extracellular Matrix | Collagen pathway analysis |
| Peptide Chemistry | Copper-binding characterization |
References
- Pickart L, Margolina A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences. View publication.
Certificate of Analysis (COA)
Documentation should establish the GHK peptide identity, copper content, purity, and actual amount of complex.
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