Description
Pinealon Technical Overview
Pinealon, also known as EDR peptide or Glu-Asp-Arg, is a synthetic tripeptide composed of L-glutamic acid, L-aspartic acid, and L-arginine.
It belongs to a family of short peptide bioregulators investigated in experimental research involving cellular signaling, peptide-DNA interactions, neuronal responses, and molecular regulatory mechanisms.
Pinealon has attracted scientific interest because of its defined three-amino-acid structure and its inclusion in studies examining cellular localization and interactions between short peptides and nucleic acids.
Proposed neuroprotective and cellular regulatory activities remain experimental and have not been established as clinically effective in humans.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | Pinealon |
| Alternative Names | EDR Peptide, Glu-Asp-Arg |
| Chemical Name | L-Glutamyl-L-aspartyl-L-arginine |
| CAS Number | 175175-23-2 |
| PubChem CID | 10273502 |
| Molecular Formula | C15H26N6O8 |
| Molecular Weight | 418.40 g/mol |
| Amino Acid Sequence | H-Glu-Asp-Arg-OH |
| One-Letter Sequence | EDR |
| Sequence Length | 3 amino acid residues |
| Peptide Classification | Short Peptide Bioregulator |
| Source | Synthetic |
| Vial Content | 5mg |
These molecular specifications describe the unmodified EDR tripeptide. Salt forms may have different molecular compositions.
Storage and Handling
- Store according to the manufacturer’s recommended stability conditions.
- Keep the container tightly sealed and protected from moisture.
- Avoid unnecessary exposure to direct light.
- Minimize temperature fluctuations during laboratory storage.
- Follow established laboratory handling procedures.
Lyophilized Format
Pinealon may be manufactured in lyophilized (freeze-dried) form.
Lyophilization reduces moisture content and can support peptide stability when appropriate storage conditions are maintained.
The physical form and stability requirements of the specific preparation should be confirmed through manufacturer documentation.
Research Use Disclaimer
Pinealon is described exclusively for laboratory research purposes.
It is not intended for human or veterinary consumption, clinical use, diagnostic applications, or therapeutic administration.
Pinealon is not FDA-approved for human therapeutic use.
Frequently Asked Questions
What Is Pinealon 5mg?
Pinealon 5mg is a research preparation of the synthetic tripeptide Glu-Asp-Arg, also known as EDR peptide.
What Is the Amino Acid Sequence of Pinealon?
The sequence is H-Glu-Asp-Arg-OH, abbreviated EDR.
What Are the CAS Number and Molecular Weight?
Pinealon has CAS number 175175-23-2 and a molecular weight of approximately 418.40 g/mol.
What Research Areas Involve Pinealon?
Pinealon has been investigated in experimental research involving short peptide transport, peptide-nucleic acid interactions, cellular stress signaling, and molecular regulation.
Is Pinealon Approved for Human Use?
No. Pinealon is not FDA-approved for human therapeutic use.
Research Overview
Pinealon has been studied in experimental research involving the molecular behavior of short synthetic peptides.
Its three-residue Glu-Asp-Arg structure provides a defined chemical sequence for investigating peptide transport, interactions with nucleic acids, and cellular responses.
Peptide Transport Research
Research involving fluorescently labeled short peptides has examined their cellular distribution and nuclear localization.
Experimental studies have investigated Pinealon alongside other peptide bioregulators in cultured cell systems.
Peptide-DNA Interaction Research
Laboratory investigations have examined interactions between short peptides and nucleic acids.
These experiments contribute to understanding potential molecular recognition mechanisms but do not establish therapeutic effects.
Neuronal Research
Pinealon has attracted scientific interest in experimental neuronal research.
Proposed relationships with neuroprotective signaling and cellular stress responses require further independent investigation.
Gene Regulation Research
Studies of short peptide bioregulators have explored possible relationships between peptide structure, chromatin interactions, and transcription-related processes.
Specific mechanisms attributed to Pinealon remain incompletely established.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| Peptide Transport | Cellular uptake and localization |
| Peptide-DNA Research | Molecular interaction assays |
| Neuronal Research | Experimental cellular responses |
| Gene Regulation | Transcription-related research |
| Peptide Chemistry | Structure-activity investigations |
References
- Fedoreyeva L.I. et al. (2011). Penetration of Short Fluorescence-Labeled Peptides into the Nucleus in HeLa Cells and In Vitro Specific Interaction of the Peptides with Deoxyribooligonucleotides and DNA. Biochemistry (Moscow). View publication.
- PubChem — Pinealon (Glu-Asp-Arg), CID 10273502.
Certificate of Analysis (COA)
Batch-specific analytical documentation should establish the peptide sequence, molecular identity, purity, and actual compound content.
For information about available documentation, contact Peptide Lives.



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