Kisspeptin-10 10mg

Description

Kisspeptin-10 Technical Overview

Kisspeptin-10 is a synthetic decapeptide corresponding to the biologically active C-terminal region of naturally occurring kisspeptin peptides.

Kisspeptins are derived from the KISS1 gene and interact with the kisspeptin receptor, known as KISS1R or GPR54.

Kisspeptin-10 has been investigated extensively in reproductive endocrinology because kisspeptin signaling is an important regulator of gonadotropin-releasing hormone (GnRH) neuronal activity.

Experimental studies have examined receptor activation, GnRH signaling, and associated reproductive hormone pathways.

Compound Specifications

The complete molecular composition depends on terminal modifications and any counterions present in the supplied preparation.

Storage and Handling

• Store according to the manufacturer’s validated stability recommendations.
• Protect the material from moisture and direct light.
• Keep containers securely closed.
• Use suitable laboratory handling procedures to maintain peptide integrity.

Lyophilized Format

Kisspeptin-10 may be prepared in lyophilized form. The stability and physical characteristics of the supplied preparation should be confirmed through manufacturer documentation.

Research Use Disclaimer

Kisspeptin-10 is not FDA-approved for human therapeutic use. This research preparation is not intended for human or veterinary administration, diagnosis, or therapeutic application.

Frequently Asked Questions

What Is Kisspeptin-10 10mg?

Kisspeptin-10 is a synthetic ten-amino-acid peptide corresponding to the active C-terminal region of kisspeptin.

What Is Its Amino Acid Sequence?

The sequence is YNWNSFGLRF-NH2.

Which Receptor Does Kisspeptin-10 Activate?

Kisspeptin-10 interacts with KISS1R, also known as GPR54.

What Research Areas Involve Kisspeptin-10?

Research includes GnRH signaling, hypothalamic activity, reproductive hormone regulation, and receptor pharmacology.

Is Kisspeptin-10 Approved for Human Use?

No. Kisspeptin-10 is not FDA-approved for therapeutic use.

Research Overview

Studies identifying the relationship between kisspeptin signaling and reproductive endocrine regulation established KISS1R as an important component of the hypothalamic-pituitary-gonadal axis.

Experimental research demonstrated that kisspeptin-related peptides can influence GnRH neuronal activity, which contributes to the regulation of downstream gonadotropin signaling.

KISS1R Receptor Research

Kisspeptin-10 activates KISS1R, a G protein-coupled receptor involved in reproductive endocrine signaling.

GnRH Signaling Research

Scientific investigations have examined kisspeptin-associated activation of GnRH neurons and related neuroendocrine responses.

Hypothalamic-Pituitary Research

Research has explored the relationship between kisspeptin activity and the regulation of luteinizing hormone and follicle-stimulating hormone pathways.

Reproductive Maturation Research

Genetic and physiological investigations have established an important role for KISS1R signaling in reproductive maturation and endocrine development.

Research Applications

References

1. Messager S, Chatzidaki EE, Ma D, et al. (2005). Kisspeptin Directly Stimulates Gonadotropin-Releasing Hormone Release via G Protein-Coupled Receptor 54. Proceedings of the National Academy of Sciences. PubMed PMID: 15665093.

Certificate of Analysis (COA)

Batch-specific documentation should establish the peptide sequence, identity, purity, and actual compound content.

For available documentation, contact Peptide Lives.