Description
IGF-1 LR3 Technical Overview
IGF-1 LR3, also known as Long R3 IGF-I, is a modified analogue of insulin-like growth factor 1.
The peptide contains an N-terminal extension and an amino acid substitution that alter its binding characteristics relative to native IGF-1.
Research has investigated IGF-1 LR3 in growth factor signaling, IGF-binding protein interactions, and cellular proliferation models.
Compound Specifications
| Property | Value |
|---|---|
| Compound Name | IGF-1 LR3 |
| Alternative Name | Long R3 IGF-I |
| Sequence Length | 83 amino acids |
| Classification | Modified IGF-1 analogue |
| Research Receptor | IGF-1R |
| Vial Content | 0.1mg |
Storage and Handling
- Follow protein-specific manufacturer storage conditions.
- Protect from moisture and contamination.
- Minimize temperature changes.
Lyophilized Format
Long R3 IGF-I may be manufactured in lyophilized form. Stability depends on formulation.
Research Use Disclaimer
IGF-1 LR3 is not FDA-approved for human therapeutic use. Not intended for human or veterinary administration.
Frequently Asked Questions
What Is IGF-1 LR3?
An extended synthetic analogue of IGF-1.
How Many Amino Acids Does It Contain?
83.
What Receptor Is Associated With It?
IGF-1R.
How Does It Differ From IGF-DES?
IGF-DES is truncated, while LR3 includes an extension and amino acid substitution.
Research Overview
Long R3 IGF-I is investigated in receptor and binding protein research.
IGF-1R Signaling
Research examines growth factor receptor activity.
Binding Protein Interactions
Experimental studies characterize altered IGFBP binding.
Cell Proliferation
Research investigates growth factor-associated cellular responses.
Research Applications
| Research Area | In Vitro Application |
|---|---|
| IGF-1R | Receptor activation assays |
| IGFBPs | Protein-binding research |
| Cell Biology | Proliferation measurements |
References
- Francis GL, Ross M, Ballard FJ, et al. (1992). Novel Recombinant Fusion Protein Analogues of Insulin-Like Growth Factor-I. Publication record.
Certificate of Analysis (COA)
Documentation should confirm sequence, molecular identity, purity, and actual content.



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